HorizonWatching

The Scientist: 2009 Top 10 Innovations

It’s been a tough year for every industry, and the life sciences are no exception. Yet companies and academic laboratories across the globe have developed innumerable new products designed to take your research to the next level. But with many lab budgets tighter than last year, which technologies are worth the investment?  via www.the-scientist.com

The top ten innovations listed in the article are

1) Pluripotency from proteins. New technique uses protein-induced stem cell technology and the specialized cells derived from it to reprogram cells to an embryonic-like state.

2) Quick pathogen ID. Breakthroughs in pathogen detection and testing basic mutation rates in viruses, forensics, and other applications

3) Manipulate cells using light. Tagging proteins to watch cellular events unfold and then manipulating those events with the molecular-level precision.

4) A camera that quantifies. The Evolve camera makes imaging data quantifiable and reproducible by measuring images in units of photoelectrons.

5) Zinc fingers create knockout rat.  ZFN technology from Sigma has numerous applications in basic research, agriculture, and possibly medical therapeutics.

6) All-in-one microscopes. New microscopes from Olympus combine illumination systems, microscopes, movable stages, and cameras all into a simple little box.

7) New sequence capture tool. New tool called HybSelect uses DNA microarrays to narrow in on regions of the genome that play an important role in a particular disease.

8) New measure of metabolism. The new XF96 Analyzer provides a comprehensive picture of cellular metabolism and how that process goes awry in disease.

9) New recipe for protein expression. Highlights a trend towards synthetic genes

10) Cell culture in 3D. $35,000 Benchtop BioLevitator combines an incubator and a centrifuge into a single unit. It is one of the first 3D cell culture systems.

Making Healthcare Smarter

Unless you are on Mars, you are aware that there’s a bunch of discussion going on now about making our Healthcare systems better.   Much of that discussion, I feel, is missing the critical topic of the IT infrastructure supporting our healthcare systems.  There needs to be more discussion on how to modernize the technology within the Healthcare systems. 

HealthCare systems should be designed to connect people to information, to experts and to each other so that collectively, we can all act proactively to better manage and deliver preventative and therapeutic care.  Our healthcare system s need better connections, better data, and faster and more detailed analysis.  It needs an integrated view of the underlying data/information and centering it on the patient, so each person "owns" his or her information, controls who access it, and has can provide that access to a networked team of collaborative care. 

We need to move away from paper records to electronic records.  This will reduce medical errors and improve efficiencies.  And more importantly, it will allow us to apply  advanced data analytics to the the vast amounts of data, to improve outcomes.

Some places for you to check out some good discussion going on these days about how technology can improve our healthcare system.

Video

The video to the right (lasts 1:41) makes the case for a smarter HealthCare System

Blogs

The following blogs are great resources on what is happening in Healthcare and IT

• HealthNex: Blogging about Healthcare & Technology since June 2005   http://healthnex.typepad.com/
• Smarter Healthcare:  Building a Smarter Planet  http://asmarterplanet.com/blog/category/smarter-healthcare
• Healthcare tag on “a smarter planet” blog http://smarterplanet.tumblr.com/tagged/healthcare
• Future of Health IT: http://www.futurehealthit.com/

Upcoming Webinar

Join IBM and University of Pittsburgh Medical Center (UPMC) on September 16th, at 12:00ET for a complimentary web seminar:  "Making Smarter Healthcare a Reality: Implications for Today's CIO.".  Dan Pelino, General Manager of IBM Healthcare and Life Sciences, along with a distinguished guest panel will share their points of view on the evolution of smarter healthcare and how the motivational forces of patient safety and quality are driving new levels of transformation.  On the guest panel is…

• G. Daniel Martich, MD, Chief Medical Information Officer and Associate Chief Medical Officer, UPMC, will discuss how UPMC embodies smarter healthcare and their transformative journey. Dr. Martich will also discuss the Center for Connected Medicine, a showcase facility for patient-centered, collaborative care.

• Sean Hogan, Vice President, Global Healthcare Delivery Systems, IBM Healthcare and Life Sciences and Peggy Rodebush, RN, MSN, Healthcare Partner, IBM Global Business Services will share the results from the soon-to-be released IBM Global CIO Study providing provocative insights on the evolution of the Healthcare CIO’s role in the organization’s business strategy and in realizing innovative, smarter healthcare.  

Websites

• IBM Healthcare and Life Sciences http://www-03.ibm.com/industries/healthcare/us/index.html
• IBM Smarter HealthCare:  http://www.ibm.com/ibm/ideasfromibm/us/smartplanet/topics/healthcare/20090223/index1.shtml
• HealthCare 2015:  http://www-03.ibm.com/industries/healthcare/us/detail/landing/G883986O04888I88.html

House Passes Wind Energy Research and Development Act of 2009

Wind energy currently makes up 2% of the total energy generation in the United States, but there is the potential for it to provide up to 20% with the right improvements in turbine technology, forecasting, energy storage, and expansion of transmission systems.

So it is great to see that the U.S. lawmakers are starting to focus on this area.  Yesterday, the U.S. House of Representatives passed the Wind Energy Research and Development Act of 2009.  The bill, if eventually signed into law, would authorize a comprehensive program to improve the efficiency, reliability and cost effectiveness of domestic wind energy systems.

The bill would authorize the Secretary of Energy to carry out a program of research and development to improve the energy efficiency, reliability, and capacity of wind turbines; optimize the design and adaptability of wind energy systems; and reduce the cost of construction, generation, and maintenance of wind energy systems.

Specifically, this program would include:

• Examination of new materials and designs to make larger, lighter, less expensive, and more reliable motor blades
• Technologies to improve gearbox performance and reliability
• Technologies to improve transmission from remotely located renewable resource rich areas
• Low-cost transportable towers greater than 100 meters in height
• Advanced computational modeling tools, control systems, blade sensors and advanced generators
• Wind technology for offshore applications
• Automation, materials, and assembly of large-scale components
• Methods to assess and mitigate the effects of wind energy systems on radar and electromagnetic fields
• Wind turbines with a maximum electric power production capacity of 100 kilowatts or less

The bill authorizes $200 million dollars per year from 2010 through 2014 for these programs.

Let’s hope this bill, or something like it, makes it way into law.

For more information

• Wind Energy Research and Development Act of 2009
• New Roadmaps for Wind and Solar Research and Development

One Million Times Smaller Than A Grain Of Sand

Get a picture in your mind of how big a grain of sand is.  Okay…got it?  Now…think of a really small object one million times smaller than that.  Okay…got that?  Now think of the significance of taking a picture of that small object.

Last week, IBM scientists announced they have successfully used an atomic force microscope (AFM) to reveal the chemical bonds within a molecule.  This is a significant announcement as this is the first time that all the atoms in a molecule have been imaged. 

The image that was taken was of a rectangular-shaped organic molecule is made up of 22 carbon atoms and 14 hydrogen atoms.  The image looks similar to the shape of molecules we all learned in chemistry classes in high school and college.  The image (a bit blurry) shows hexagonal shapes of the five carbon rings are clear and even the positions of the hydrogen atoms around the carbon rings can be seen.

To understand the significance of the first ever image, you have to understand how small the molecule was that was imaged.  The space between the carbon rings is only 0.14 nanometers across, which is roughly one million times smaller than the diameter of a grain of sand.  Now that is small!

So what does this announcement have to do with you?  Perhaps not much, but it means a big deal to future generations that will be in a world made up of very small (nano) things.  The IBM scientists say that this research could have a huge impact of the field of nanotechnology, which seeks to understand and control some of the smallest objects known to mankind.  

"Scanning probe techniques offer amazing potential for prototyping complex functional structures and for tailoring and studying their electronic and chemical properties on the atomic scale.”  - IBM Researcher Gerhard Meyer

More pictures are here on Flickr.  A video is on YouTube here.  And check out IBM’s announcement “IBM Scientists First to Image the Anatomy of a Molecule”

8 Emerging CleanTech Investment Areas

A new report is claiming that, with an aggressive infrastructure investment, eight emerging technologies could meet 60 % of new energy demand by 2020.  It is also claiming that we could abate more CO2 than is necessary for climate stabilization in just 10 years.  

The report, titled  "The Gigaton Throwdown", was developed with the support of many, many people who are tied to the cleantech industry.  The effort was led, in part, by Sunil Paul, who is a founder of Silicon Valley’s Spring Ventures.

The report estimates that if annual global private investment in cleantech tripled between now and 2020, clean energy investments would be in line with fossil-fuel investments.   It is a lofty goal, but the authors say that if we are able to shift investment into ready cleantech solutions, the results would be world changing:  climate mitigation, energy security and 5 million new jobs planetwide.

The report highlights the eight emerging clean technology solution areas that are ready for investment and could yield the stated goals.

1. Biofuels
2. Building Efficiency
3. Concentrating Solar Power
4. Construction Materials
5. Geothermal
6. Nuclear
7. Solar Photovoltaics
8. Wind

According to the report each of the eight solutions listed above could feasibly deliver one giagaton of global energy, and each could avoid one gigaton of emissions from being discharged into the atmosphere by 2020, thus the idea for the name of the report.

Apparently the authors considered plug-in electric vehicles , but the projected adoption of this technology is predicted to be too slow to have an impact by 2020.

For more information:

• Access the 150 page report via the pdf file "The Gigaton Throwdown"
• Check out the Gigaton website
• Watch this Videos
• Read this Announcement Letter

Looking to 2050: Ten Challenges For The Human Race

Peter Schwartz is recognized internationally as a futurist and strategist.  He honed his skills at Royal Dutch/Shell Group in London, where he led a widely respected scenario planning effort.   He has written a number of interesting books about the future, including The Art of the Long View. 

This past May he gave the commencement address at Rensselaer Polytechnic Institute.  During the address, he outlined ten longer term challenges for the human race as we look forward to the next 40-50 years.  He encouraged the graduates to come up with innovative solutions to these challenges. 

The top challenges Schwartz outlined are:

1. Creating long-term solutions to meet our energy demands sustainably.
2. Launching a bio-industrial revolution with sustainable manufacturing.
3. Understanding and enhancing the human brain to avert age-related impairments.
4. Improving agriculture to reduce costs and increase its energy and water efficiency.
5. Building sustainable cities through better urban planning and "smart architecture”.
6. Stimulating job growth and economic development.
7. Fusing the technological with the spiritual and aesthetic dimensions of human culture.
8. Advancing technological instruments to drive scientific discovery forward.
9. Harnessing biological tools to advance human evolution.
10. Discovering new ways to lower the costs and environmental impact of space flight and development.  

The list above is an interesting list.  I am not sure that these are the top ten most important challenges, but each of the above ten are certainly important. 

Some comments…

• Energy tops his list and it is hard to argue that it should not be there.  I can’t see the demand for energy going down anytime soon and we need to figure out how to transition to clean energy. 
• Improving agriculture processes in developing nations will have have a significant impact on the economy and quality of life.
• Building smarter and sustainable cities is a very large challenge as the number of megacities grow and grow.
• Number 9 on his list, “Harnessing biological tools to advance human evolution” sounds both scary and beneficial at the same time.
• Regarding number 10, with announced plans to go back to the moon and to Mars, we will need innovative ways to travel through space and live at the destinations we travel to.

It is worth pointing out that many on the list kind of fall under the push for a smarter planet.

If you want to read a transcript of Peter Schwartz’s commencement address, check out http://news.rpi.edu/update.do?artcenterkey=2585

Can you think of any other challenges Schwartz’s list?  The only one that comes to my mind right now is the never ending desire to live in a world free from war and conflict, but I don’t suppose for one minute that that will be solved in the next 40-50 years.

Science: Top 10 Scientific Breakthroughs of 2008

With the year 2008 wrapping up to an end, the Journal of Science has released its annual list of top ten scientific breakthroughs of 2008 in their December 19th issue.  

1. Cellular Reprogramming:  A method that produces "made-to-order" cell lines by reprogramming cells from ill patients.   As this was number one on their list, there is an article that provides more detail on it: Breakthrough of the Year: Reprogramming Cells 
2. Exoplanets:  Using a special telescope techniques, for the first time the astronomers were able to directly observe planets orbiting other stars.
3. Expanding The Catalog Of Cancer Genes:  Researchers have been able to sequence genes from two deadliest cancer cells, pancreatic cancer and glioblastoma.  They turned up dozens of mutations that remove the brakes on cell division and send the cell down the path to cancer.
4. New Mystery Materials:  An entirely new second family of high-temperature superconductors were discovered. These materials consisted of iron compounds instead of copper-and-oxygen-compounds.
5. Watching Proteins At work:  It was a pleasant surprise for the biochemists to watch proteins bind to their targets, switch a cell’s metabolic state and contribute to a tissue’s properties.
6. Toward Renewable Energy On Demand:  In order to store excess energy generated from part-time sources like wind and solar power, researchers have found a new promising tool using a "cobalt-phosphorus catalyst".
7. The Video Embryo:  In 2008, researchers observed in unprecedented detail the dance of cells in a developing embryo, recording and analyzing movies that trace the movements of the roughly 16,000 cells that make up the zebrafish embryo by the end of its first day of development.
8. "Good" Fat, Illuminated:  Scientists have been able to morph "good" brown fat, which burns "bad" white fat to generate heat for the body, into muscle and vice versa.  This has led to a new approach to treat obesity...
9. Calculating The Weight Of The World:  Physicists have been successful in calculating the mass of proton and neutron from the standard model which describes most of the visible universe’s particles and their interactions.
10. Faster, Cheaper Genome Sequencing: Researchers have been able to report a sequencing technology that is much cheaper and speedier.  The technique can be applied from woolly mammoths to human cancer patients.

For more information, check out the special section that report on the top breakthrough and nine runners-up.   Online extras include an online video presentation and a special Breakthrough edition of the Science Podcast.

The Phoenix Has Landed...with 7 Important Scientific Instruments

Nasa's Phoenix landed over a week ago on Mars.   You can read up on the landing at http://uanews.org/node/19859

The mission has a number of objectives, including 1) Studying the history of water on Mars by examining water-ice below the martian surface and 2) Determining if the  martian arctic soil could support life.  By digging into the soil and water-ice just below the surface and analyzing the chemistry of the soil and ice with robust instruments, scientists will better understand the history of the martian arctic.   You can read up more on the mission at: http://www.nasa.gov/mission_pages/phoenix/main/index.html

I was curious about what type of scientific instruments were aboard the lander so I did some research.   Here is a list of the key instruments on board.

1. Mars Descent Imager.  The job of this instrument is already done.  During Phoenix’s descent,  it took a series of wide-angle, color images of the landing site and surrounding area all the way down to the surface.
2. Surface Stereoscopic Imager.  This instrument is a high tech stereo camera that will provide high-resolution, stereoscopic, panoramic images of the surrounding landscape.  It will help identify potential geological content, provide range maps in support of digging operations, and make atmospheric dust and cloud measurements.
3. Robotic Arm.   Once a digging site is picked, the Robotic Arm will dig and collect soil and water-ice samples.
4. Robotic Arm Camera.  This camera is attached to the Robotic Arm just above the scoop.  It will take close-up, full-color images of (1) the ground/rocks/landscape, (2) potential soil and water-ice samples, (3) samples that have been collected in the scoop and (4) the floor and side-walls of the trenches that have been dug in order to examine fine-scale texturing and layering. 
5. Thermal and Evolved Gas Analyzer.  This unique instrument will serve both as a high-temperature oven and a mass spectrometer instrument that scientists will use to analyze ice and soil samples.  Once the Robotic Arm delivers samples to this instrument, the oven temperature will increase.  The gases that are boiled out of the sample will be piped to a mass spectrometer for chemical analysis.
6. Microscopy, Electrochemistry, and Conductivity Analyzer (MECA).  This is a combination of several scientific instruments all wrapped into one.  By mixing small amounts of soil in water, MECA can determine important chemical properties like acidity, saltiness, and composition.  MECA has a built-in microscope that can examine the soil grains to help determine their origin and mineralogy.  It also has special probes that when stuck into the soil determine the water and ice content.
7. Meteorological Station.  This instrument records the daily weather using temperature and pressure sensors, as well as a light detection and ranging instrument.  This information will help scientists determine how water is cycled between the solid and gas phases on the martian artic plains.

You can read up more on the instruments at http://www.nasa.gov/mission_pages/phoenix/spacecraft/index.html

30 Companies To Watch In The Space Industry

In the last two posts, I have blogged on the emerging space industry, which is in the early stages of being commercialized.  While governmental organizations will still take the lead on space exploration, I believe private companies are now taking the lead in the commercialization of space. 

Based on the research I have done these past two days, I have assembled a list of 30 companies below that I feel are the ones to watch.  These are the companies that I feel will be leaders in the research, development, and implementation of space related commerce that will happen over the next 2-3 decades..  The list is presented in alphabetical order and links to the company websites provided. 

1. Andrews Space.  The company mission statement says "Andrews will be a catalyst in the development, exploration, and commercialization of emerging space markets by providing innovative, entrepreneurial aerospace solutions to our commercial, civil, and military customers."  Andrews' technical competencies include product/system development, space system design, rapid prototyping, propulsion system design, systems engineering, and business analysis.  Andrews Space has already has received an Air Force contract to flesh out its Hybrid Launch Vehicle concept.  http://www.andrews-space.com/ 
2. Armadillo Aerospace: Armadillo Aerospace is an aerospace startup company based in Mesquite, Texas.  Its initial goal is to build a manned suborbital Ansari X-Prize-class spacecraft in order to grab some of the suborbital tourism market.   It's plan is to use computer-controlled liquid-oxygen rockets to launch people 300,000 above the Earth. http://www.armadilloaerospace.com 
3. Bigelow Aerospace: This start-up company is pioneering work on expandable space station modules that have a flexible outer shell.  The shell is contractible for launch.  Once in orbit, the module is inflated, allowing greater work, play, and living area for astronauts.  http://www.bigelowaerospace.com 
4. Blue Origin: Blue Origin is a privately-funded company, founded in 2000 and owned by Amazon.com founder Jeff Bezos .  Blue Origin has begun construction on a spaceport in West Texas and is at work on a reusable space launch vehicle.  http://www.blueorigin.com/ 
5. Boeing:  Boeing's  Space Exploration division, headquartered in Houston, is a leading global supplier of reusable and human space systems and services.  Boeing has designed, developed, built, and operated human and robotic space vehicles as well as supporting hardware.  Projects included Gemini, Apollo, Skylab, Space Shuttle and International Space Station (ISS).   Check out their website at http://www.boeing.com/defense-space/space_exploration/index.html 
6. CubeSat. The CubeSat program strives to provide practical, reliable, and cost-effective launch opportunities for small satellites and their payloads.  Check out the community website at http://www.cubesat.info/    CubeSat projects are popping up at universities everywhere.  Cubesat kits are provided by http://www.cubesatkit.com/ 
7. Energia Space: Russian-based Energia has been successfully carrying out the most daring rocket and space projects requiring revolutionary engineering solutions for many years.  As a large organization, they are involved in almost all areas of space technology, transportation, and exploration.  Energia   http://www.energia.ru/english/index.html 
8. European Space Agency: The European Space Agency (ESA) is an inter-governmental organization  with 17 member states. Headquartered in Paris ESA has a staff of about 1,900.  The agency has a full line-up of projects and is involved in almost all aspects of space exploration, transportation, and business.  http://www.esa.int 
9. Interorbital Systems: Interorbital Systesm is a small company that makes spacecraft components:  Interorbital is attempting to launch the first spacecraft that can carry six passengers into orbit for seven days. The $30 million Neptune Spaceliner, which could take flight in 2008, is funded by sales of rocket designs and guidance systems. Additional funds will come from selling payload space on the company's Sea Star microsatellite launcher, due to blast off in 2007.  http://www.interorbital.com/ 
10. Japanese Space Agency:   On October 1, 2003 three independent organizations (ISAS, NAL and NASDA) were merged into one independent administrative institution: the Japan Aerospace Exploration Agency (JAXA).  The agency, like the European Space Agency (ESA), is focused on many important projects for furture space transportation, but on a smaller scale than NASA or ESA.  Check out their vision for 2025 at the following URL  http://www.jaxa.jp/2025/index_e.html 
11. Kayser-Threde:  Founded in 1967, Kayser-Threde is a leading systems house providing high-technology solutions for the industrial, aerospace and scientific sectors.   These include applications and solutions in manned and unmanned space missions, data measurement and management, telematics, optics and process control.  http://www.kayser-threde.com/ 
12. LiftPort:  LiftPort, Inc. was established in 2003 with the goal of building a space elevator.  The company's mission is simple: to build a complete space transportation infrastructure based around the space elevator concept.  This is an ambitious goal and one the company hopes to acheive before 2020.  Check out the company website at http://www.liftport.com 
13. Lockheed Martin.  Lockheed Martin's Space Systems Company is a recognized leader in the design, production and integration of launch vehicles and systems, spacecraft for telecommunications, remote sensing and space science.  Lockheed's Orion Crew Vehicle will provide a state-of-the-art human space flight system capable of safely transferring astronauts to and from the International Space Station (ISS), the Moon, Mars and other destinations beyond low earth orbit (LEO).   Read more on the Orion Crew Vehicle at http://www.lockheedmartin.com/products/Orion/index.html
14. NASA.  NASA needs little explanation...and there is not doubt it needs to be on this list!  Go to their website at http://www.nasa.gov/externalflash/nasa_gen/index.html 
15. Orbital Sciences: Orbital Sciences develops launch systems.  Orbital is a publicly traded company with revenues of around $700 million and a main office in Virginia.  Its Mojave facility is focused on the deployment of its Pegasus rocket system, which is designed to be drop-launched from an aircraft flying at 40,000 feet. That makes it possible to place satellites in low orbit for $31 million, a fraction of the cost of vertical launches. Pegasus has already flown 36 times.  http://www.orbital.com/ 
16. Rocketplane Kistler. This company has developed the Kistler K-1 reusable launch vehicle. The K-1 is a fully reusable aerospace vehicle, designed to deliver payloads to orbit and provide a low-cost alternative to single-use launch vehicles. The company intends the K-1 to become the reliable, low-cost provider of launch services for commercial, civil, and military payloads destined for Low Earth Orbit (LEO), Medium Earth Orbit (MEO) and Geosynchronous Earth Orbit (GEO), as well as for cargo resupply and recovery flights to and from the International Space Station (ISS).   Read more at http://www.kistleraerospace.com/ 
17. Scaled Composites:  Scaled Composites develops suborbital spacecraft.  Famed aerospace engineer Burt Rutan is developing SpaceShipTwo, a seven-passenger suborbital flier  and he's planning a world-class manufacturing facility in Mojave to churn out the ships.  The first five ships--which are rumored to be as plush as Gulfstream jets--will be flown exclusively by Branson's Virgin Galactic out of Mojave in 2008, although he does eventually expect to sell his ships to other operators. Branson says each ticket for a few minutes of weightlessness will initially cost about $200,000 and that more than 100 passengers have already signed up.  http://www.scaled.com/ 
18. Space Adventures.  Founded in 1998, Space Adventures Ltd. is all about pace tourism.  The company offers it's customers Orbital Flights, Suborbital Flights, Spaceflight Training, and Space-related Flight Adventures.  Want to go on a flight?  Read more at  http://www.spaceadventures.com/ 
19. SpaceDev: SpaceDev produces micro and nano satellites, hybrid rocket-based orbital Maneuvering and orbital Transfer Vehicles (MoTVs) as well as safe sub-orbital and orbital hybrid rocket-based propulsion systems.  SpaceDev has begun designing a reusable, piloted, sub-orbital space ship of their own that could be scaled up to safely and economically transport passengers to and from low earth orbit, including the International Space Station. The name of the vehicle is the “SpaceDev Dream Chaser".   Check out their website at http://www.spacedev.com 
20. Space Exploration Technologies. Space Exploration Technologies (SpaceX) is a private company.  It develops launch vehicles and provides launch services.  Their mission is to revolutionize the commercial space industry.  The company was founded by Elon Musk, whose previous businesses (PayPal and Zip2 Corp.) gave him the wherewithal to get into the space-for-hire market.  SpaceX is developing the Falcon launch vehicle family, which is being designed to provide breakthrough advances in reliability, cost, flight environment and time to launch.  http://www.spacex.com/ 
21. Space Island Group: The Space Island Group mission is to develop a stand-alone, commercial space infrastructure supporting the broadest possible range of manned business activities in Low Earth Orbit (LEO) for the 21st century and beyond.   SIG will build large, commercial space stations to be leased to a wide range of tenants as factories, hotels and entertainment complexes.  SIG also has plans to will also build large, commercial space stations to house their solar satellite assembly and maintenance crews. Some stations, resembling the one depicted in the 1968 film “2001: A Space Odyssey”, will be leased to a wide range of tenants as factories, hotels and entertainment complexes.  SIG’s target is to supply half the world’s electricity generation and distribution, currently a $2 trillion annual market.  http://www.spaceislandgroup.com/home.html 
22. Spacehab:  Spacehab provides commercial and government space services with three primary business units.  Spacehab has built research modules for the space shuttle and is also offering its Apex line of spacecraft.   Apex is designed to execute a wide range of missions, including delivering experiments or supplies to the International Space Station, providing a platform for on-orbit research, or supporting orbital operations,  Read more at  http://www.spacehab.com/ 
23. Space Services: Space Services is a 30 year old company that has developed a reliable and consistent launch program for cremated remains.  They offer a number of different space flights, including earth orbit, lunar flight, and deep space.   The company is not just about memorial flights, as they have done work for the government on next generation micro satellite and propulsion technologies (e.g. including solar sails).  Read more at  http://www.spaceservicesinc.com/ 
24. Surrey Satellite Technology. SSTL, was founded over 20 years ago and was the first professional organization to offer low-cost small satellites.  The company's stated mission is to lead the small satellite industry Today, SSTL employs over 200 staff and is considered the most experienced small satellite supplier in the world.   http://www.sstl.co.uk/ 
25. The Planetary Society:  The Planetary Society was founded in 1980 by futurists Carl Sagan, Bruce Murray, and Louis Friedman.  The stated focus is to inspire humans to explore space.  Dedicated to exploring the solar system and seeking life beyond Earth, The Planetary Society is non-governmental and nonprofit and is funded by the support of its members.  Not just an education body, the Planetary Societary develops cutting-edge space technology and promotes private ventures in space.  Read more at http://www.planetary.org 
26. Trans Lunar Research: Trans Lunar Research is working on moon habitation related projects with a small group of volunteers.  This nonprofit foundation, run out of Interorbital's office, has an ambitious goal: to establish a civilian station on the surface of the Moon that will become a base for lunar mining, energy extraction, and exploration. Funded by private donations,  Trans Lunar plans to issue grants to support the development of propulsion systems, habitation technology, and oxygen extraction equipment.  http://www.translunar.org/ 
27. t/Space: Transformational Space Corporation is developing a piloted spacecraft to take people and cargo to and from space for NASA, other government agencies, and private customers.  t/Space is currently working on designs for an air-launched four-person capsule termed the Crew Transfer Vehicle, or CXV.    http://www.transformspace.com/ 
28. Universal Space Lines: This company was formed in 1996.  The company vision is enabling low-cost access to space and therefore it has focused on the development of reusable launch vehicles as the only viable, long-term solution for reducing the cost of access to space.   http://www.spacelines.com 
29. Virgin Galactic: Virgin Galactic, part of Sir Richard Branson's Virgin Group, plans to offer sub-orbital spaceflights and later orbital spaceflights to the paying public.   Virgin Galactic plans to fly 500 passengers a year at about US$200,000 each, to an altitude of over 100 km, with a total weightless time of 7 minutes.  The website provides more information at http://www.virgingalactic.com/ 
30. Xcor Aerospace:  Xcor Aerospace is a small company that makes rocket engines.  Xcor's EZRocket is a reusable engine powered by liquid oxygen and rubbing alcohol that has already been flight-tested. Applications range from propelling airplanes in the Rocket Racing League (which gets under way in September) to powering the Xerus, a suborbital spaceliner being developed with funding from private investors and the government.  http://www.xcor.com/

These last three posts I have blogged about space business.  I've brought it to our attention because I truly believe that "the train has left the station"....meaning that the commercialization of space is happening right now.   .

Emerging Technology Innovations In HealthCare and Life Sciences

IBM issued a press release about 3 weeks ago titled  "IBM Unveils Top Technology Innovations That Will Shape the Future of Healthcare and Life Sciences Over the Next Decade".  Perhaps you missed it too.  Here is a summary.

IBM announced a series of emerging innovations that have the potential to dramatically shift the landscape of healthcare and life sciences solutions for patients, hospitals, pharmaceutical companies, and the general public. These innovations are based on new research breakthroughs and emerging technologies from IBM's Labs as well as through a legacy of storage, server and technology innovation and deep roots in the healthcare industry.

Over the next five to ten years, IBM predicts that the healthcare industry will experience radical shifts brought about by the following trends and technology innovations:

• Secure sharing of patient data:  As we move toward the universality of electronic health records, the secure sharing of patient information and the interoperability of systems across regions, countries and the world become increasingly important. 
• Fully-informed diagnosis:  The ability to share information among doctors, health care providers and hospitals will enable clinicians to compare records and diagnoses while preserving patient privacy, paving the way to faster, more comprehensive care 
• Speeding drugs to market:  Advances in data mining and analysis will enable the development of targeted therapeutic drugs and medical treatments. 
• Stemming the spread of pandemics:  New modeling tools will allow public health decision-makers to quickly identify and potentially prevent the spread of pandemics.

More information is available in the press release.  I can think of some others that did not make the list, like performance metrics, benefit/payment process transformation, human augmentation, robotic surgery, and simulation applications.